Everton Agnes

Theoretical and computational neuroscience

We are constantly stimulated by what we see, hear, smell, taste, and touch. Our brains take these complex inputs and transform them into actions and thoughts through what we call input/output functions. Every part of the brain, from single neurons to entire brain regions, can be described by such functions. Finding their accurate description has the potential to change lives, both through improved treatments for mental illness as well as better algorithms for artificial intelligence.

Our aim is to mathematically describe how the brain translates sensory input into behaviour at various spatial and temporal scales. We focus on how inputs onto a single neuron generate its output activity, and how neuronal networks process complex information.

Computers, as well as pen and paper, are the tools that, through mathematical analysis and simulations, will allow us to unveil how the brain processes information.

Simulations allow us to compare a large variety of different scenarios, which are impossible to access via modern experimental technologies. Experimental work is essential for us to build our models, and in turn, our models will serve as inspiration for future experiments in a continuing incremental loop. The result is that, together, theory and experiments will help us shine a light on the mysteries of the brain, with countless applications to improve our lives, from health to technology.

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Everton Agnes